![Frontiers | Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition Frontiers | Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition](https://www.frontiersin.org/files/Articles/622473/fcvm-07-622473-HTML/image_m/fcvm-07-622473-g002.jpg)
Frontiers | Targeting PAI-1 in Cardiovascular Disease: Structural Insights Into PAI-1 Functionality and Inhibition
![Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) - Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) -](https://abstracts.isth.org/wp-content/uploads/2020/06/p_1120_01073.jpg)
Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) -
![Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) - Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) -](https://abstracts.isth.org/wp-content/uploads/2020/06/p_1120_01070.jpg)
Down-regulation of Plasminogen Activator Inhibitor-1 (PAI-1) by in vivo Thrombin Generation and Subsequent Formation of Activated Protein C (APC) in Carriers of the Factor V Leiden (FVL) and Prothrombin 20210G>A Mutation (PTM) -
![IJMS | Free Full-Text | Role of Plasminogen Activator Inhibitor Type 1 in Pathologies of Female Reproductive Diseases IJMS | Free Full-Text | Role of Plasminogen Activator Inhibitor Type 1 in Pathologies of Female Reproductive Diseases](https://www.mdpi.com/ijms/ijms-18-01651/article_deploy/html/images/ijms-18-01651-g001-550.jpg)
IJMS | Free Full-Text | Role of Plasminogen Activator Inhibitor Type 1 in Pathologies of Female Reproductive Diseases
![Coronary thrombus in 34-year-old female patient with 4G/4G polymorphism in the PAI-1 gene - ScienceDirect Coronary thrombus in 34-year-old female patient with 4G/4G polymorphism in the PAI-1 gene - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2405818115300386-fx1.jpg)
Coronary thrombus in 34-year-old female patient with 4G/4G polymorphism in the PAI-1 gene - ScienceDirect
![IJMS | Free Full-Text | PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea? IJMS | Free Full-Text | PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea?](https://www.mdpi.com/ijms/ijms-23-05516/article_deploy/html/images/ijms-23-05516-g001.png)
IJMS | Free Full-Text | PAI-1: A Major Player in the Vascular Dysfunction in Obstructive Sleep Apnea?
![A scheme of the angotensin/®brinolysis pathway, illustrating the key... | Download Scientific Diagram A scheme of the angotensin/®brinolysis pathway, illustrating the key... | Download Scientific Diagram](https://www.researchgate.net/profile/Nina-Rogenhofer/publication/5388931/figure/fig1/AS:281591587852326@1444148074628/A-scheme-of-the-angotensin-Rbrinolysis-pathway-illustrating-the-key-role-of-angiotensin_Q320.jpg)
A scheme of the angotensin/®brinolysis pathway, illustrating the key... | Download Scientific Diagram
![The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk - ScienceDirect The effect of the plasminogen activator inhibitor-1 4G/5G polymorphism on the thrombotic risk - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0049384807003623-gr1.jpg)